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IIT Bombay Develops Platform to Convert Fatty Acids into Ring-Shaped Bioactive Molecules, Published in Nature

Target:UPSC GS-IIIMPSCTeachingSSC GAPrelims HighMains Medium
15 Jul 2026
~2 min
Source: Indian Express
Key Data:15 mg from 15 kg plant materialNature journal
Bodies:IIT BombayBhabha Atomic Research Centre (BARC)
Practice MCQs from today's news ▸
What This Article Covers

1.IIT Bombay develops a general platform to convert straight-chain carbon compounds (like fatty acids) into ring-shaped molecules, solving a long-standing synthetic chemistry problem.

2.The breakthrough, published in Nature, was led by Prof. Debabrata Maiti and involved students and collaborators from BARC. It reduces steps, chemical waste, and cost.

3.Examiners may ask about the significance of the method being a 'general platform' applicable to many bioactive molecules, and the specific synthesis of muricatacin from soursop.

The Big Picture
Prelims · HighMains · Medium

IIT Bombay scientists have developed a novel chemical method to convert common straight-chain fatty acids into complex ring-shaped molecules, a process that traditionally required multiple steps. This breakthrough, published in Nature, could accelerate drug discovery and make it cheaper and more sustainable. The method has been used to synthesize muricatacin, an anti-cancer compound found in soursop, in the lab.

Exam Lens

Quick Exam Facts From News

JournalNature
Lead ResearcherProf. Debabrata Maiti, IIT Bombay
Key Molecule SynthesizedMuricatacin (anti-cancer)
Natural SourceLaxman phal (soursop)
Efficiency of Natural Extraction15 mg from 15 kg plant material

1-Minute Revision

  • ›Journal: Nature
  • ›Lead Researcher: Prof. Debabrata Maiti, IIT Bombay
  • ›Target this Data: 15 mg of muricatacin from 15 kg of plant material (natural extraction inefficiency).
  • ›Target this Institution: IIT Bombay (lead research institution) and Bhabha Atomic Research Centre (collaborator).
  • ›Target this Journal: Nature (high-impact journal for publication).

Mastered this topic? Test your knowledge with a full MCQ quiz.

Practice exam-style questions, track your score, and strengthen your recall.

Q1Static LinkageEasy

Which institution led the research published in Nature that developed a new method to convert fatty acids into ring-shaped molecules?

Q2Statement-basedHard

Consider the following statements:

1. The new method converts straight-chain carbon compounds into ring-shaped molecules.

2. The method is specific only to the synthesis of muricatacin.

3. The research was published in the journal Nature.

Which of the statements given above is/are correct?

Q3Data-centricMedium

According to the article, how much muricatacin is obtained from natural extraction of 15 kg of soursop plant material?

Q4Application/ImpactMedium

What is the primary advantage of the new synthetic method developed by IIT Bombay over traditional methods?

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