Science_TechChemistry
News 0 of 21

IIT Bombay Develops Faster Method to Convert Fatty Acids into Complex Ring Molecules for Drug Discovery

Target:UPSC GS-IIIMPSCTeachingPrelims HighMains Medium
06 Jul 2026
~2 min
Source: Indian Express
Key Data:15 mg muricatacin from 15 kg plant materialPublished in Nature
Bodies:IIT BombayBhabha Atomic Research Centre (BARC)
Practice MCQs from today's news ▸
What This Article Covers

1.IIT Bombay team led by Prof Debabrata Maiti published a new method in Nature to convert straight-chain fatty acids into ring-shaped molecules more efficiently.

2.The method uses a specially developed chemical compound to selectively target a specific carbon atom, reducing the multi-step process to fewer steps with less waste.

3.The team synthesized muricatacin (an anti-cancer compound from soursop) and other bioactive molecules, demonstrating broad applicability for faster, cheaper drug development.

The Big Picture
Prelims · HighMains · Medium

IIT Bombay scientists have developed a novel, efficient method to convert simple fatty acids into complex ring-shaped molecules—key building blocks for drugs. This breakthrough published in Nature reduces steps, cost, and waste, and could accelerate drug discovery from traditional medicine systems like Ayurveda.

Exam Lens

Quick Exam Facts From News

Lead ResearcherProf Debabrata Maiti, IIT Bombay
Journal PublishedNature
Key Molecule SynthesizedMuricatacin (anti-cancer, from soursop)
Collaborating InstitutionBhabha Atomic Research Centre (BARC)
Natural Source of MuricatacinLaxman phal (soursop)

1-Minute Revision

  • ›Lead Researcher: Prof Debabrata Maiti, IIT Bombay
  • ›Journal Published: Nature
  • ›Target this Data: The method was published in Nature journal.
  • ›Target this Institution: IIT Bombay (lead) and Bhabha Atomic Research Centre (collaborator).
  • ›Target this Molecule: Muricatacin (anti-cancer from soursop) was synthesized.

Mastered this topic? Test your knowledge with a full MCQ quiz.

Practice exam-style questions, track your score, and strengthen your recall.

Q1Static LinkageEasy

Which institution collaborated with IIT Bombay in the research on converting fatty acids into ring-shaped molecules?

Q2Statement-basedHard

Consider the following statements regarding the new method developed by IIT Bombay:

1. The method converts straight-chain fatty acids into ring-shaped molecules in a single step.

2. The method is a general process applicable to a wide array of organic compounds, not limited to a single molecule.

3. The team synthesized muricatacin, a compound with anti-cancer properties that is naturally found in soursop.

Which of the statements given above is/are correct?

Q3Data-centricMedium

How much muricatacin is naturally obtained from 15 kg of soursop plant material according to the article?

Q4Application/ImpactMedium

What is the primary significance of the new method developed by IIT Bombay for drug discovery?

All 20 MCQs ▸
You finished this topic
Explore Related Topics
Related Current Affairs
Science & Tech Current Affairs

DAE Proposes Reducing Land Need for 220 MWe Nuclear Reactors to 90 Hectares

The Department of Atomic Energy informed Parliament that land requirement for 220 MWe small nuclear reactors could be reduced from 330 hectares to about 90 hectares, subject to radiological impact assessment. This is part of India's push for Small Modular Reactors (SMRs) and opening the nuclear sector to private participation, with exclusion zones also proposed to be relaxed. The move is critical for energy security and decarbonization of hard-to-abate industries.

Science & Tech Current Affairs

CSIR-IICT Develops IND-Ready Phytopharmaceutical from Gymnema sylvestre for Diabetic Foot Ulcers

CSIR-IICT has developed a phytopharmaceutical from the medicinal plant Gymnema sylvestre for diabetic foot ulcers, a major complication of diabetes. The technology has been transferred to Mumbai-based Viridis Biopharma for clinical development and regulatory approvals, including CDSCO and USFDA. This marks a significant step in India's evidence-based botanical drug discovery and academia-industry collaboration.

Science & Tech Current Affairs

NPCIL Commences Fuel Loading at RAPP-8: 4th Indigenous 700 MWe PHWR in Fleet Mode

NPCIL has started initial fuel loading (IFL) at Unit 8 of Rajasthan Atomic Power Project (RAPP-8), a 700 MWe indigenous pressurised heavy water reactor (PHWR). This marks a major step in India's fleet-mode nuclear expansion, with commercial operation expected in 2026-27. For exams: understand PHWR technology, AERB's role, and the commissioning sequence (IFL → FAC → power generation).

Science & Tech Current Affairs

China Launches 4 Orbital Rockets in 45 Hours; Targets 28,000 Satellites via Qianfan & SatNet

China launched four rockets in 45 hours from three launch sites, deploying satellites for its Qianfan (15,000 satellites) and SatNet (13,000 satellites) broadband megaconstellations. This highlights the rapid expansion of China's space sector, combining state and private players, and the strategic push for low Earth orbit satellite networks.

Science & Tech Current Affairs

ISRO & ESA Extend Cooperation Until 2032; Add Human & Robotic Exploration, Space Weather

ISRO and ESA have extended their cooperation agreement by five years until January 8, 2032, and broadened it to include human and robotic exploration and space weather. This signals deepening international space collaboration and has implications for India's Gaganyaan mission and future lunar/Venus exploration.

Science & Tech Current Affairs

Gaganyaan Parachute System: 2 Drogue & 3 Main Chutes with Multi-Stage Reefing for Safe Re-entry

India's Gaganyaan human spaceflight mission relies on a complex parachute system with multiple stages and redundancy. Understanding the science behind drogue and main chute deployment, reefing mechanisms, and materials like Kevlar/Nomex is critical for UPSC Science & Technology and Defence questions. The article details how ADRDE (Agra) developed these parachutes and testing via RTRS at TBRL Chandigarh.

Science & Tech Current Affairs

ISRO-ESA Renew Space Cooperation Till 2032; Focus on Space Weather & Robotic Exploration

India (ISRO) and the European Space Agency (ESA) have renewed their space cooperation agreement until 2032, focusing on space weather monitoring and human/robotic exploration. This strengthens India's Gaganyaan and Chandrayaan missions and ensures long-term collaboration in critical areas like satellite safety and deep-space exploration.

Science & Tech Current Affairs

IN-SPACe Releases Planned Re-entry Guidelines: Safety Threshold 1 in 10,000, Mandates Third-Party Liability Insurance

IN-SPACe has released new guidelines for planned re-entry of space objects, establishing a safety threshold of 1 in 10,000 risk to humans and mandating third-party liability insurance for private operators. This is crucial for India's human spaceflight mission Gaganyaan and the growing private space sector.