Science_TechHealth
News 19 of 25

India Gets First Disease-Modifying Alzheimer's Drug Leqembi After CDSCO Nod

Target:UPSC GS-IIIMPSCSSC GATeachingPrelims HighMains MediumStatic GK Link
05 Aug 2026
~2 min
Source: The Hindu
Key Data:8.8 million dementia patients (2023)Prevalence 7.4%Projected to nearly double by 2036Leqembi (lecanemab)CDSCOHumanised monoclonal antibody
Bodies:CDSCOEisaiAIIMSUSC
Practice MCQs from today's news ▸
What This Article Covers

1.Eisai launched Leqembi (lecanemab) in India for early Alzheimer's (MCI and mild dementia) after CDSCO marketing authorisation.

2.It is a humanised monoclonal antibody that targets aggregated amyloid-beta to clear plaques and reduce further deposition.

3.India has ~8.8 million dementia patients (age 60+, 2023), with prevalence 7.4%, projected to nearly double by 2036.

The Big Picture
Prelims · HighMains · Medium

Eisai's Leqembi (lecanemab), India's first disease-modifying therapy for early Alzheimer's, has been launched after CDSCO approval. This marks a shift from symptomatic to disease-modifying treatment, but challenges of early diagnosis, biomarker infrastructure, and affordability remain significant.

Exam Lens

Quick Exam Facts From News

Drug NameLeqembi (lecanemab)
CompanyEisai (Japan)
Regulatory BodyCDSCO
IndicationEarly Alzheimer's (MCI and mild dementia)
MechanismHumanised monoclonal antibody targeting amyloid-beta
India Dementia Burden (2023)8.8 million (age 60+, prevalence 7.4%)
Projected Dementia (2036)Nearly double from 2023

1-Minute Revision

  • ›Drug Name: Leqembi (lecanemab)
  • ›Company: Eisai (Japan)
  • ›Target this Data: 8.8 million Indians aged 60+ living with dementia in 2023 (prevalence 7.4%)
  • ›Target this Nodal Body: CDSCO (Central Drugs Standard Control Organisation) under Ministry of Health and Family Welfare
  • ›Target this Legal Point: Marketing authorisation from CDSCO for a disease-modifying therapy (DMT)

Mastered this topic? Test your knowledge with a full MCQ quiz.

Practice exam-style questions, track your score, and strengthen your recall.

Q1Static LinkageEasy

Which regulatory body granted marketing authorisation for Leqembi in India?

Q2Statement-basedHard

Consider the following statements regarding Leqembi:

1. It is a humanised monoclonal antibody that targets aggregated amyloid-beta.

2. It is indicated for patients with moderate to severe Alzheimer's disease.

3. Patients need confirmation of amyloid pathology through cerebrospinal fluid or serum biomarkers before therapy.

Which of the statements given above is/are correct?

Q3Data-centricMedium

According to the AIIMS-USC LASI study cited in the article, how many Indians aged 60 years and above were living with dementia in 2023?

Q4Application/ImpactMedium

What is the primary therapeutic objective of Leqembi (lecanemab) as described in the article?

All 25 MCQs ▸
You finished this topic
Explore Related Topics
Related Current Affairs
Science & Tech Current Affairs

CDSCO Approves Qdenga: India's First Dengue Vaccine to be Distributed by Dr Reddy's from 2027

India’s first approved dengue vaccine Qdenga will enter the private market in 2027 via Dr Reddy’s, after CDSCO approval in July 2026. The vaccine is effective against all four serotypes, requires no pre-vaccination screening, and shows 61.2% efficacy against dengue and 84.1% against hospitalization. This is a landmark step in India's fight against dengue.

Science & Tech Current Affairs

Proposed Patient Data Collective (PDC) Model for Rare Diseases in India Inspired by Amul Cooperative

A new proposal suggests creating a Patient Data Collective (PDC) for rare diseases in India, modeled on the Amul dairy cooperative. This collective would pool patient data to accelerate drug discovery and clinical trials, addressing the challenge of small patient populations for rare diseases.

Science & Tech Current Affairs

CDSCO Approves Qdenga Dengue Vaccine for Ages 4-60; Dr. Reddy's to Distribute in Private Market by 2027

India's first approved dengue vaccine, Qdenga (TAK-003), developed by Takeda, received CDSCO marketing authorisation in July 2026 for ages 4-60. Dr. Reddy's will promote and distribute it in the private market from the first half of 2027, while Takeda retains public market rights. This marks a critical step in addressing India's 11-fold rise in dengue cases over two decades.

Science & Tech Current Affairs

CSIR-IICT Develops IND-Ready Phytopharmaceutical from Gymnema sylvestre for Diabetic Foot Ulcers

CSIR-IICT has developed a phytopharmaceutical from the medicinal plant Gymnema sylvestre for diabetic foot ulcers, a major complication of diabetes. The technology has been transferred to Mumbai-based Viridis Biopharma for clinical development and regulatory approvals, including CDSCO and USFDA. This marks a significant step in India's evidence-based botanical drug discovery and academia-industry collaboration.

Science & Tech Current Affairs

IISc SraVaani: India's First Open-Source Speech Recognition Model for 65 Languages

IISc's SPIRE Lab, in collaboration with ARTPARK and Google, has released SraVaani – the first multilingual Indian speech recognition model trained on 65 languages and dialects. It extends ASR to 45 underserved regional languages, potentially benefiting 25 crore people. This marks a major step in inclusive AI for India's linguistic diversity.

Science & Tech Current Affairs

SCTIMST Unveils Chitra Core Stent: 30-40% Less Metal, Reduces Restenosis & Thrombosis

SCTIMST has launched 'Chitra Core', a fully indigenous coronary stent with a patented design that uses 30-40% less metal than conventional stents, aiming to reduce complications like restenosis and thrombosis. A second stent, 'Chitra TiN' with a titanium nitride coating, is ready for global pre-clinical trials.

Science & Tech Current Affairs

Stem Cell Therapy for Autism Restricted to Clinical Trials; Health Ministry Advisory Follows SC Order

The Union Health Ministry has reiterated that stem cell therapy for Autism Spectrum Disorder (ASD) can only be offered as part of approved clinical trials, not as routine or commercial treatment. This follows a landmark Supreme Court judgment in January 2026 that examined the issue. The advisory reinforces existing regulations under the Clinical Establishments Act, 2010, and the National Guidelines for Stem Cell Research, 2017.

Science & Tech Current Affairs

ISRO Launches EOS-05: India's First Geo-Imaging Satellite in Geosynchronous Orbit; SC Invokes Article 142 to Quash CJP Protest Cases

A day of high exam relevance: ISRO successfully launched EOS-05, India’s first dedicated geo-imaging satellite in geosynchronous orbit, breaking a failure streak. The Supreme Court used its extraordinary power under Article 142 to close cases linked to CJP protests, raising important constitutional questions. Other key updates include OpenAI’s new autonomous AI model, Manipur’s NRC-first demand for Census deferral, mistrust in GDP data, and Tata Chemicals’ Kenya dispute.