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CDSCO Approves Qdenga: India's First Dengue Vaccine – Efficacy & Pricing Concerns Remain

Target:UPSC GS-IIIMPSCTeachingSSC GAPrelims HighMains HighStatic GK Link
24 Jul 2026
~2 min
Source: The Hindu
Key Data:Over 40 countries licensedWHO prequalification2 doses, 3 months apartDENV-2, DENV-1, DENV-3, DENV-4 serotypesTIDES trial negative efficacy for DENV-3 hospitalisation in seronegative children
Bodies:CDSCOWHOTakeda
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What This Article Covers

1.CDSCO approves Qdenga – India's first dengue vaccine – licensed in 40+ countries and WHO prequalified.

2.Vaccine efficacy varies: high against DENV-2, moderate against DENV-1, uncertain against DENV-3 and DENV-4 in seronegative individuals.

3.Two-dose regimen and high cost may limit access for at-risk populations; government must negotiate lower pricing.

The Big Picture
Prelims · HighMains · High

India's drug regulator CDSCO has approved Qdenga, the first dengue vaccine in the country, developed by Takeda. However, the vaccine shows variable efficacy across four serotypes, with weaker protection against DENV-3 and DENV-4 in dengue-naive individuals. Pricing concerns and logistical challenges in administering two doses to migrant workers pose significant hurdles for effective rollout.

Exam Lens

Quick Exam Facts From News

Regulatory BodyCDSCO (Central Drugs Standard Control Organization)
Vaccine DeveloperTakeda (Japan)
WHO PrequalificationYes
Dose Regimen2 doses, 3 months apart
Primary ConcernWeaker efficacy against DENV-3 & DENV-4 in seronegative; negative efficacy in TIDES trial for DENV-3 hospitalisation

1-Minute Revision

  • ›Regulatory Body: CDSCO (Central Drugs Standard Control Organization)
  • ›Vaccine Developer: Takeda (Japan)
  • ›Target this Data: Qdenga requires 2 doses administered 3 months apart.
  • ›Target this Nodal Body: CDSCO (Central Drugs Standard Control Organization) – the approving authority.
  • ›Target this Legal Point: WHO Prequalification – a key regulatory milestone for vaccine procurement.

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Q1Static LinkageEasy

Which regulatory body in India approved the Qdenga dengue vaccine?

Q2Statement-basedHard

Consider the following statements regarding the Qdenga dengue vaccine:

1. Qdenga is the first dengue vaccine approved in India.

2. Qdenga provides equal protection against all four dengue serotypes.

3. The vaccine requires two doses administered three months apart.

Which of the statements given above is/are correct?

Q3Data-centricMedium

According to the article, in how many countries has the Qdenga dengue vaccine been licensed?

Q4Application/ImpactMedium

What is a major concern regarding the rollout of the Qdenga dengue vaccine in India?

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