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KARS-Net 2025 Report: 73% ESBL E. coli, 43% Carbapenem-Resistant Klebsiella in Kerala

Target:UPSC GS-IIIMPSCSSC GATeachingPrelims HighMains MediumStatic GK Link
20 Sept 2026
~2 min
Source: The Hindu
Key Data:65,849 isolates55 laboratories14 districts59 institutions73% ESBL E. coli43% carbapenem-resistant Klebsiella
Bodies:KARS-NetGovernment Medical College, ThiruvananthapuramNCDCWHO
Practice MCQs from today's news ▸
What This Article Covers

1.Kerala's KARS-Net 2025 antibiogram, covering 65,849 patient isolates from 55 labs across 14 districts, confirms AMR is now widespread beyond ICUs.

2.Critical data: E. coli 73% ESBL-positive, Klebsiella 43% carbapenem-resistant in blood, and Shigella 93% ciprofloxacin-resistant — indicating community-level resistance.

3.This is the 7th year of Kerala's AMR surveillance model (KARSAP), now feeding data into WHO's GLASS and NCDC, making it a national model for AMR containment.

The Big Picture
Prelims · HighMains · Medium

Kerala's 2025 antimicrobial resistance (AMR) surveillance data reveals a critical public health crisis: drug-resistant bacteria are now the norm, not the exception, in both hospital and community settings. With E. coli showing 73% ESBL positivity and Klebsiella 43% carbapenem resistance, this report signals an urgent need for antibiotic stewardship and policy intervention.

Exam Lens

Quick Exam Facts From News

Surveillance NetworkKARS-Net (Kerala AMR Surveillance Network)
Coordinating InstitutionDept. of Microbiology, Govt. Medical College, Thiruvananthapuram
Data Coverage65,849 isolates, 55 labs, 14 districts, 59 institutions
E. coli ESBL (blood)73%
Klebsiella Carbapenem-resistant (blood)43%
Shigella Ciprofloxacin-resistant93%
Colistin Resistance (overall)0.1%
MRSA (blood)33%

1-Minute Revision

  • ›Surveillance Network: KARS-Net (Kerala AMR Surveillance Network)
  • ›Coordinating Institution: Dept. of Microbiology, Govt. Medical College, Thiruvananthapuram
  • ›Target this Data: 73% E. coli ESBL, 43% Klebsiella carbapenem-resistant, 93% Shigella ciprofloxacin-resistant, 0.1% colistin resistance
  • ›Target this Nodal Body: Kerala Antimicrobial Resistance Surveillance Network (KARS-Net) under Kerala Antimicrobial Resistance Strategic Action Plan (KARSAP)
  • ›Target this Legal Point: WHO's Global Antimicrobial Resistance Surveillance System (GLASS) framework

Mastered this topic? Test your knowledge with a full MCQ quiz.

Practice exam-style questions, track your score, and strengthen your recall.

Q1Static LinkageEasy

Which institution coordinates the Kerala Antimicrobial Resistance Surveillance Network (KARS-Net)?

Q2Statement-basedHard

Consider the following statements:

1. According to the 2025 KARS-Net report, 73% of E. coli isolated from blood were producing ESBL enzymes.

2. Carbapenem resistance in Klebsiella species from blood isolates was 52% in the same report.

3. Colistin remains largely effective in Kerala with an overall resistance profile of 0.1%.

Which of the statements given above is/are correct?

Q3Data-centricMedium

According to the KARS-Net 2025 report, what percentage of Shigella species showed resistance to ciprofloxacin?

Q4Application/ImpactMedium

What is the primary public health implication of the finding that community-acquired Shigella shows 93% ciprofloxacin resistance?

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