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IARC Classifies Three WHO Essential Medicines as Group 1 Carcinogens: Hydrochlorothiazide, Voriconazole, Tacrolimus

Target:UPSC GS-IIIMPSCTeachingSSC GAPrelims HighMains MediumStatic GK Link
05 Aug 2026
~2 min
Source: The Hindu
Key Data:Group 1HydrochlorothiazideVoriconazoleTacrolimusWHO Model List of Essential Medicines
Bodies:IARCWHO
Practice MCQs from today's news ▸
What This Article Covers

1.IARC classifies hydrochlorothiazide, voriconazole, and tacrolimus as 'carcinogenic to humans' (Group 1).

2.All three drugs are on the WHO Model List of Essential Medicines and are prescribed to millions worldwide.

3.Experts urge patients not to discontinue treatment due to the significant therapeutic benefits.

The Big Picture
Prelims · HighMains · Medium

IARC, the WHO cancer research agency, has classified three widely used drugs—hydrochlorothiazide, voriconazole, and tacrolimus—as Group 1 carcinogens. Despite this, experts stress that patients should not stop treatment as the benefits for hypertension, fungal infections, and organ transplant rejection far outweigh the cancer risk. The drugs are on the WHO Model List of Essential Medicines and are commonly prescribed in India.

Exam Lens

Quick Exam Facts From News

IARC ClassificationGroup 1 (Carcinogenic to humans)
Drugs ClassifiedHydrochlorothiazide, Voriconazole, Tacrolimus
WHO ListModel List of Essential Medicines

1-Minute Revision

  • ›IARC Classification: Group 1 (Carcinogenic to humans)
  • ›Drugs Classified: Hydrochlorothiazide, Voriconazole, Tacrolimus
  • ›Target this Data: Group 1 classification for Hydrochlorothiazide, Voriconazole, Tacrolimus
  • ›Target this Nodal Body: IARC (International Agency for Research on Cancer) under WHO
  • ›Target this Legal Point: WHO Model List of Essential Medicines

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Practice exam-style questions, track your score, and strengthen your recall.

Q1Static LinkageEasy

Which agency classified the three common medicines as carcinogenic to humans?

Q2Statement-basedHard

Consider the following statements regarding the three drugs classified by IARC:

1. All three drugs are on the WHO Model List of Essential Medicines.

2. Hydrochlorothiazide is used to treat life-threatening fungal infections.

3. Experts have urged patients to immediately stop taking these medicines.

Which of the statements given above is/are correct?

Q3Data-centricEasy

How many common medicines were classified as Group 1 carcinogens by IARC in this news?

Q4Application/ImpactMedium

Why do experts advise patients not to stop taking these medicines despite the IARC classification?

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