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ICMR-NIRWoH, IIT Bombay Develop Indigenous Placenta-on-Chip Platform for Pregnancy Research

Target:UPSC GS-IIIMPSCTeachingPrelims HighMains High
04 Jul 2026
~2 min
Source: The Hindu
Key Data:Published in BiofabricationICMR-NIRWoH (formerly ICMR-NIRRCH)IIT BombayFunctions: hormone production, nutrient transfer, waste exchange, selective barrier
Bodies:ICMR-National Institute for Research on Women's Health (ICMR-NIRWoH)Indian Institute of Technology Bombay (IIT Bombay)
Practice MCQs from today's news ▸
What This Article Covers

1.ICMR-NIRWoH (Mumbai) and IIT Bombay jointly developed a lab-grown placenta-on-chip platform that reproduces maternal-fetal interface functions.

2.The device is scalable, compatible with standard lab workflows, and simpler than existing microfluidic systems.

3.Potential applications include studying pregnancy complications (gestational diabetes, pre-eclampsia, fetal growth restriction) and evaluating placental drug transfer.

The Big Picture
Prelims · HighMains · High

Indian researchers from ICMR-NIRWoH and IIT Bombay have developed an indigenous 'placenta-on-chip' platform that mimics key functions of the human placenta – hormone production, nutrient transfer, waste exchange, and selective barrier. This human-relevant model can revolutionise pregnancy research, drug safety testing, and reduce animal experimentation.

Exam Lens

Quick Exam Facts From News

Lead InstitutionsICMR-NIRWoH (formerly ICMR-NIRRCH), Mumbai & IIT Bombay
Journal of PublicationBiofabrication
Key Functions RecreatedHormone production, nutrient transfer, waste exchange, selective barrier
Potential Disease ModelsGestational diabetes, pre-eclampsia, fetal growth restriction
Key ResearchersDeepak Modi, Anshul Bhide, Abhijit Majumder, Sourav Mukherjee

1-Minute Revision

  • ›Lead Institutions: ICMR-NIRWoH (formerly ICMR-NIRRCH), Mumbai & IIT Bombay
  • ›Journal of Publication: Biofabrication
  • ›Target this Data: Published in journal 'Biofabrication'
  • ›Target this Nodal Body: ICMR-National Institute for Research on Women's Health (ICMR-NIRWoH), formerly ICMR-NIRRCH
  • ›Target this Application: Modeling gestational diabetes by simulating hyperglycaemic conditions

Mastered this topic? Test your knowledge with a full MCQ quiz.

Practice exam-style questions, track your score, and strengthen your recall.

Q1Static LinkageEasy

Which two institutions jointly developed the indigenous placenta-on-chip platform mentioned in the news?

Q2Statement-basedHard

Consider the following statements regarding the placenta-on-chip platform:

1. It reproduces hormone production, nutrient transfer, waste exchange, and selective barrier function.

2. The platform requires sophisticated microfluidic equipment and continuous perfusion systems.

3. The study was published in the journal 'Biofabrication'.

Which of the statements given above is/are correct?

Q3Data-centricMedium

In which scientific journal was the study on the placenta-on-chip platform published?

Q4Application/ImpactMedium

What is a key advantage of the Indian placenta-on-chip platform over many existing systems?

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